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Humatrope Overview:

Benefits. Side Effects, How to Use and Where to Buy

Humatrope is an injectable form of human growth hormone (HGH) made by Eli Lilly.

Humatrope® is a man-made form of HGH made by using recombinant DNA (rDNA). Humatrope is used to treat children who do not make enough growth hormone on their own, have Turner Syndrome, idiopathic short stature, have SHOX deficiency, and/or were born smaller than normal for the number of weeks of pregnancy and do not catch up in height by 2 to 4 years of age.

In adults, Humatrope is used to treat growth hormone deficiency that began in childhood and has continued, or in adulthood that has occurred as the result of pituitary disease, hypothalamic disease, surgery, radiation therapy, or trauma or age-related hormone loss.

Indications and Contraindications for Humatrope


According to its manufacturer, Humatrope® should not be taken by:

  • People with serious complications after having open heart surgery, abdominal surgery, serious injuries involving many body systems, or with life-threatening breathing problems
  • Children with Prader-Willi syndrome who are severely obese or have a history of severe breathing problems
  • People with active cancer
  • People who have had an allergic reaction to growth hormone
  • People with diabetic disease of the retina (the lining in the back of the eyeball)
  • Children who have closed growth plates in their bones


Before accepting a prescription for Humatrope®, tell your doctor about all of your prescription and over-the-counter drugs, including cyclosporine, hormone replacement therapy, insulin or other diabetes medications, drugs containing steroids, or drugs for seizures. In addition:

  • Your doctor should check your blood sugar regularly while you are taking Humatrope®, especially if you have diabetes, pre-diabetes, or risk factors for diabetes. New cases of type 2 diabetes have been reported in patients taking Humatrope®.
  • Tell your doctor if you have any visual changes accompanied by headache, nausea, and/or vomiting while taking Humatrope®. This may be a sign of increased pressure in the brain.
  • Adults may retain water during Humatrope® treatment. This may be brief and may increase with higher doses of Humatrope®.
  • If you have hypoadrenalism and are on glucocorticoid replacement therapy, your doctor may increase your dosage when you initiate growth hormone treatment.
  • Your doctor should test your thyroid function periodically during Humatrope® therapy. Thyroid hormone treatment may need to be started or adjusted.
  • Fracture in the ball of the hip joint can occur in children who have endocrine problems and in children who have rapid growth. Any child taking Humatrope® who develops a limp or complains of hip or knee pain should be seen by a doctor to check for this.
  • Progression of curvature of the spine (scoliosis) can occur in children who have rapid growth. Humatrope® has not been shown to increase the occurrence of this condition. If the child has scoliosis, the doctor should carefully monitor the progression of the scoliosis during Humatrope® treatment.
  • Cases of pancreatitis (inflammation of the pancreas) have been reported rarely in children and adults receiving growth hormone. Consult a doctor if you develop abdominal pain while taking Humatrope®.
  • You should rotate your injection sites to avoid the breakdown of skin and fat. Seek prompt medical attention for any allergic reaction you experience to the injection of Humatrope®.

See your medication’s insert or complete Trusted sourceHighlights of Prescribing Information HumatropeEli Lilly and CompanyGo to sourcePrescribing Information for a complete list of potential drug interactions.

Humatrope Benefits and Side Effects

Humatrope is FDA-approved for the treatment of growth hormone deficiency in adults and children. It is generally regarded as safe. However, like any drug or prescription medication, Humatrope injections have benefits as well as potential side effects.

Benefits List

Clinical trials have demonstrated that Humatrope is therapeutically equivalent to the human growth hormone produced by the pituitary gland.

In people with growth hormone deficiency, Humatrope has been shown in clinical trials to – be therapeutically equivalent to Human Growth Hormone of pituitary origin and achieves equivalent effects in the stimulation of linear growth. In addition to tissue growth, other documented benefits of Humatrope include:

  • Skeletal Growth
  • Cell Growth
  • Organ Growth
  • Increased protein metabolism
  • Improved carbohydrate metabolism
  • Improved Lipid Metabolism
  • Improved Mineral Metabolism – particularly resulting in an increase in bodily potassium and phosphorus levels

Side Effects List

Humatrope injections are FDA approved for the treatment of growth hormone deficiencies in children and adults. Humatrope is generally regarded as safe. However, as with any prescription medication, it has some potential side effects.

See your medication’s insert for a complete list of potential side effects.

Your prescription for Humatrope will be tailored to best meet your particular goals and lifestyle. You will be carefully monitored over the course of your treatment with Humatrope, so any chance of side effects should be kept to a minimum. Tell your doctor if you are experiencing any of these or other side effects while taking Humatrope.

More common – According to the manufacturer, the most common side effects of Humatrope are:

  • Injection site reactions
  • Allergic reactions to the diluent
  • Hypothyroidism

Less common – some of the potentially severe, though less common side effects of Humatrope® include:

  • Swelling
  • Joint pain
  • Muscle pain
  • Carpal tunnel syndrome
  • Unusual skin sensations and high blood sugar

See your medication’s insert or the Trusted sourceHighlights of Prescribing Information HumatropeEli Lilly and CompanyGo to sourcePrescribing Information for a complete list of potential side effects.

Your prescription for Humatrope will be tailored to best meet your particular goals and lifestyle. You will be carefully monitored over the course of your treatment with Humatrope®, so any chance of side effects should be kept to a minimum. Tell your doctor if you are experiencing any of these or other side effects while taking Humatrope®.

In Case of Overdose

Overdose of Humatrope® could lead to hypoglycemia and subsequently to hyperglycemia. Long-term overdosage could result in signs and symptoms of gigantism and/or acromegaly consistent with the known effects of excess growth hormone.

As with any medication, in case of accidental overdose, seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Keep Humatrope® and all prescription medications out of the reach of children.

How much does Humatrope Cost?

Depending on your dosage option, Humatrope injections can cost anywhere between $1,000.00 – $5,700.00.

How and Where to Buy Humatrope

You cannot buy the Humatrope® Miniquick injectable device online or anywhere else, for the matter, without a doctor’s prescription.

If your goal is to get a prescription for an HGH pen such as the Humatrope® Miniquick online, fill out our online medical history form. Or you can use the “contact us” or “chat” features on this page to schedule a consolation to see if you qualify for a prescription for Humatrope.

How to Use the Humatrope

Only use Humatrope® exactly as you are instructed to by your doctor or pharmacist. Humatrope® is available in 6 mg, 12 mg, and 24 mg cartridges for use in the HumatroPen® injection device. You will be shown exactly how to administer your Humatrope® injections.

  • Use exactly as prescribed by your doctor.
  • Do not use in larger or smaller amounts or for longer than recommended
  • Follow the directions on your prescription label
  • Use a different place on your body each time you give the injection
  • Do not inject this medicine into skin or muscle that is red, sore, infected, or injured

To further assist with the Humatrope® injection process, the manufacturer has provided a complete set of user manuals for the Trusted sourceHow do I use the HumatroPen?LillyGo to sourcepen and Trusted sourceHow do I use the HumatroPen?LillyGo to sourcevial/syringe forms of Humatrope®. A multi-chapter how to use Humatrope® instructional video can also be accessed from Trusted sourceHow do I use the HumatroPen?LillyGo to sourcethis page of the manufacturer’s website.

Dosage information*

The daily dosage of Humatrope® varies by your age, weight, and the condition it is being prescribed for. According to the Prescribing Information provided by the National Institutes for Health, Humatrope® should be administered subcutaneously as follows:

For pediatric patients

The recommended weekly dosages in milligrams (mg) per kilogram (kg) of body weight (given in divided doses 6 to 7 times per week) are:

  • Pediatric GH deficiency: 0.18 to 0.30 mg/kg/week
  • Turner syndrome: Up to 0.375 mg/kg/week
  • Idiopathic short stature: Up to 0.37 mg/kg/week
  • SHOX deficiency: 0.35 mg/kg/week
  • Small for gestational age: Up to 0.47 mg/kg/week

For adult Growth Hormone Deficiency

Either a non-weight-based or a weight-based dosing regimen may be followed, with doses adjusted based on treatment response and IGF-I concentrations.

  • Non-weight-based dosing: A starting dose of approximately 0.2 mg/day (range, 0.15-0.30 mg/day) may be used without consideration of body weight and increased gradually every 1-2 months by increments of approximately 0.1-0.2 mg/day.
  • Weight-based dosing: The recommended initial daily dose is not more than 0.006 mg/kg (6 μg/kg); the dose may be increased to a maximum of 0.0125 mg/kg (12.5 μg/kg) daily.

*Dosing information is provided for informational purposes only and should not be construed as any kind of instructions for use. Consult your physician or pharmacist for guidance regarding your particular dose of Humatrope®

Storage Information

According to the manufacturer, Humatrope HGH requires refrigeration before and after mixing. Do not place Humatrope in the freezer or subject it to temperatures below 36 degrees Fahrenheit. Humatrope comes supplied in powder form and requires mixing before use. Once mixed and in liquid form, Humatrope vials are good for no more than 14 days. The HGH in the cartridges will last up to 28 days. After that, discard the Humatrope as directed by the medication disposal laws in your community. Always inspect the Humatrope solution before use. Do not use Humatrope HGH if it has a cloudy or discolored appearance or contains any particles or crystals. Discard Humatrope if it is past the expiration date.

Humatrope Results 1-6 Months

What to Expect During the First Month

During your first month of using Humatrope, almost as soon as that first dose enters your bloodstream, your body reacts and begins to change in a positive way. As month 1 of your HGH program progresses, your growth hormone levels will increase, the production and release of IGF increases, and in about two weeks, you will notice a real significant difference. You will find that you are sleeping better, you will see increases in your energy level and overall vitality. As you reach the end of your first month of growth hormone therapy, you will feel like a much different person. You will feel stronger. You will start to look better as skin health improves and muscles begin to tighten.

Other Results After 1 Month May Include:

  • Improved cognition and a lifting of “mental fogginess”
  • Improved focus and concentration
  • Better mood, fewer feelings of anxiety and depression
  • Improved self-confidence
  • Slight increases in exercise capacity

Two Months of Humatrope Therapy Results

As you enter your second month of growth hormone therapy, the changes in your physical appearance will become much more obvious. Your skin will have a definitive more healthy and more youthful “glow.” You will notice a definite improvement in muscle tone. You will be able to exercise for longer periods at a time, which will only further improve your “before” and “after” results. Belly fat should start to diminish. You may even notice an improvement in your eyesight, particularly your night vision.

Other Results After 2 Months May Include

  • Stronger hair and nails
  • Improved metabolism – increased ability to burn fat resulting in more energy
  • Increased sex drive

Humatrope Results After 3 Months

Once you have been on Humatrope therapy for three months, now you will start to see some of the most dramatic changes in your body from when you first started. At twelve weeks out, you will look and feel physically much stronger. Bone density will have significantly improved to the point where you are more flexible and are experiencing less joint stiffness or joint pain. As you continue through month three, you will continue to see improvements in your sex drive and sexual performance.

Other Results After 3 Months May Include

  • Further improvement to memory, focus, and other cognitive functions
  • Women may experience a reduction in PMS and menopausal symptoms
  • Continued improvements to exercise capacity
  • Improved immune function resulting in greater resistance to sickness and disease
  • Increased improvements to skin and hair health
  • Greater motivation improved productivity at work

Humatrope Results After 4 Months

As you come out of your third month of growth hormone therapy and enter your fourth, this is when you experience your peak results. Fat loss will be significant, as will be your improvement in lean muscle. You will likely look and feel more “fit” than you have in years. You will experience most if not all the known benefits of HGH replacement, such as:

  • More energy
  • Increased stamina
  • Healthy skin and hair
  • Less disrupted sleep
  • Lower cholesterol and increased heart health

Other Results After 4 Months May Include

  • Maximum improvement in energy, weight loss, bone, skin, hair, and nail health
  • Significantly reduced joint pain
  • Increased endurance
  • Continued improvements in mental function
  • Improved cardiac function and heart health

Humatrope Results After 5 and 6 Months May Include

As you go through month 5 of HGH therapy and by the end of your sixth month, you will have made significant improvements. All of your results from the past few months will keep building, and you’ll experience:

  • Improvement to overall body tone and appearance.
  • Increased muscle mass.
  • Lowered cholesterol and triglycerides.
  • At least a 10% overall reduction in body fat and a 10% increase in lean muscle mass.
  • Significantly improved vitality, energy, and stamina.

Humatrope Alternatives

Humatrope is just one of several types of growth hormone our doctors prescribe. Like Humatrope, all HGH injections are some form of the prescription drug somatotropin. They differ only in their available dosages and delivery methods.

We only work with legitimate pharmacists that provide our patients with one of the name brands of prescription HGH.

Besides Humatrope, we also prescribe these popular brands of injectable HGH:

  • Genotropin
  • Omnitrope
  • Norditropin
  • Zomacton
  • Saizen
  • Serostim
  • Sorptive

Now that you know a lot more about the Humatrope, why not contact us today, and find out if it, or one of the other types of HGH injections we prescribe, is right for you?


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