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Sermorelin Therapy Results

Sermorelin Therapy Results

January 19, 2022 sermorelin

Results of Sermorelin Therapy.For certain qualifying patients, sermorelin can produce remarkable before and after results for patients suffering from age-related growth hormone deficiency.

Sermorelin belongs to a class of compounds called secretagogues. As a group, secretagogues stimulate the “secretion” of specific hormones. In the case of sermorelin, it is a synthetic duplicate of naturally occurring Growth Hormone Releasing Hormone or GHRH that stimulates your pituitary gland to increase the output of human growth hormone (HGH).

HGH is essential for growth, health, and well-being. However, the pituitary gland’s ability to produce HGH declines as you age. This decrease in pituitary function is often related to the depletion of Growth Hormone Releasing Hormones. Supplemental GHRH in the form of prescription sermorelin therapy has been shown to make up for this loss, increase the production of HGH, and have several “before and after benefits.”

What Are the Benefits of Sermorelin Therapy?

Sermorelin therapy has been shown to have many positive results for overall health and wellness. Sermorelin has been studied and shown to be quite effective in treating age-related decline of growth hormone levels.

Sermorelin is an FDA-approved prescription medication used to treat adult-onset growth hormone deficiency (AGHD) by stimulating your pituitary gland to make and release more growth hormone.

For many patients, sermorelin is considered to be a safe and effective alternative to growth hormone injections. Because of its proven ability to increase HGH production and output, sermorelin therapy improves your metabolism, your immune system, and your body’s ability to replace and repair damaged and dying cells.

Over the course of several months of treatment for patients receiving sermorelin therapy have reported many sermorelin benefits, such as improvements in:

  • Sleep patterns
  • Libido
  • Strength/Energy/stamina
  • Immune system functioning
  • Bone health
  • Skin and nail health (tighter skin, thicker nails)
  • Growth of lean muscle mass/reduction of fat

The Month By Month Result You Can Expect from Sermorelin Therapy

Sermorelin therapy is usually prescribed for a course of six months. After your first six-month program of sermorelin injections, you will be reevaluated to see if you need to continue therapy.

While you may see some of sermorelin’s benefits within the first few weeks of therapy, sermorelin therapy is designed to be cumulative over time, with “before and after” results increasing as you progress through the course of your sermorelin treatment. Here is a month-by-month breakdown of the benefits you can expect to achieve from prescription sermorelin injections.

Month 1Within the first few weeks of sermorelin injections, you will be sleeping better; you will see increases in your energy level and overall vitality. By the 3rd or 4th week, you may see an improvement in sexual desire and sexual performance.
Into the 2nd MonthYour results of sermorelin injections after two months will include an overall leaner look, a reduction in body fat, and your skin and hair will take on a more youthful appearance. You should find your feelings of “mental fog” clearing and be able to focus more.
Month 3Your results of sermorelin injections after 12-14 weeks will have you looking and feeling significantly improved. Many of the symptoms that may have brought you in for sermorelin therapy in the first place will have vanished or have been substantially reduced. You will be stronger, more flexible, you will feel less joint pain, and you should also see an improvement in your overall physical and emotional well-being.
Month 4After 3 months and into your 4th, the results of your sermorelin injections will include more fat loss, and your muscle gain will be very significant. This is the time of your peak results of sermorelin injections.
Into Month 5After month five, this is when most patients have their “before” and “after” pictures taken. You will likely be very surprised at how you looked before you started sermorelin therapy and how you look now!
After Completing Month 6Once you have completed six months of sermorelin injections, you will have achieved your maximum results. You will be a new person who can enjoy:

  • Increased energy
  • Improved sex life
  • Improved mental acuity
  • Improved muscle tone

How to Achieve Long-Lasting Sermorelin Therapy Results

Sermorelin therapy is given over the course of many weeks – usually for a period of three to six months, depending on your age, gender, presenting symptoms, medical history, and lifestyle.

One of the advantages of sermorelin therapy is that the gains you make tend to remain even after you stop taking sermorelin.

However, you will be given diet, fitness, and lifestyle counseling after the completion of your sermorelin therapy to help maintain the positive results you have achieved.

What Do the Medical Studies Say About the Benefits of Sermorelin Therapy?

There have been several sermorelin studies to date that validate the use of sermorelin as an alternative to HGH to treat GHD in some cases.

One of the earliest studies to suggest that sermorelin could be a viable alternative to HGH was published in 1996, which established that sermorelin could have similar therapeutic effects as HGH when prescribed for children who were failing to achieve growth milestones. Trusted sourceOnce daily subcutaneous growth hormone-releasing hormone therapy accelerates growth in growth hormone-deficient children during the first year of therapy. Geref International Study GroupOxford University PressGo to sourceThat study concluded,”[sermorelin] administered as a once-daily dose of 30 micrograms/kg GHRH.(1-29), s.c., was effective in increasing height velocity in GH-deficient children.”

A 2006 study published in the medical journal Trusted sourceSermorelin: A better approach to management of adult-onset growth hormone insufficiency?NCBIGo to sourceClinical Interventions in Aging concluded that peptide therapies such as sermorelin have fewer side effects and, in many cases, can be preferable to human growth hormone, particularly when sermorelin is prescribed for “anti-aging.”

A study looking at the Trusted sourceEffects of single nightly injections of growth hormone-releasing hormone (GHRH 1-29) in healthy elderly menPubMedGo to sourcebenefits of GHRP therapy for elderly men concluded that sermorelin injections “may increase muscle strength, and it alters baseline relationships between muscle strength and muscle bioenergetics in a manner consistent with a reduced need for anaerobic metabolism during exercise.”

HGH is released in “pulses.” These pulses are at their highest at night during sleep. It has been found that overweight males exhibit fewer nightly pulses of HGH. A Trusted sourceEffects of a Growth Hormone-Releasing Hormone Analog on Endogenous GH Pulsatility and Insulin Sensitivity in Healthy MenOxford University PressGo to source2011 study found that the use of “GHRP analogs” similar in chemical structure to sermorelin effectively increased the nightly release of HGH in overweight men.

These are just a few examples of the multitude of clinical studies on the benefits of sermorelin. Taken together, these sermorelin studies help validate sermorelin’s safety and efficacy in stimulating the production of human growth hormone and that it is a viable alternative -in some cases – to growth hormone therapy.

Now that you know a lot more about the before and after results of sermorelin therapy, why not contact us today and find out more about the many life-changing benefits of growth hormone therapy?


A growth hormone deficiency (GHD) occurs when your body does not produce enough human growth hormone (HGH). Both children and adults can suffer from growth hormone deficiency. 

Adults, as well as kids, can suffer from GHD. This is why doctors refer to two different categories or types of growth hormone deficiency:

  • Child-onset GHD, which is present at birth or starts in childhood. It can be carried into adulthood.
  • Adult-onset GHD, which develops in adulthood. Adult-onset GHD is sometimes also referred to as “age-related GHD.”

Sermorelin is part of the family of growth hormone-releasing agents. As a releasing agent, sermorelin stimulates your pituitary gland to produce more of your own natural growth hormone. Generally speaking, sermorelin is less expensive and has fewer possible side effects than growth hormone therapy.

Human growth hormone (HGH) is a critical hormone involved in cell and tissue growth, produced by the pituitary gland. HGH peptides such a sermorelin stimulate the pituitary gland to make HGH. Since the purpose of HGH peptide therapy is to increase the production of HGH, generally speaking, the two therapies have the same benefits. The differences basically lie in their ability to achieve said benefits. In some cases, GHRP therapy alone is enough to treat your symptoms of growth hormone deficiency. Sometimes peptide therapy is used in conjunction with growth hormone replacement.

The main advantage of alternative HGH therapies, if you qualify, is the cost. If your symptoms of growth hormone deficiency can be effectively managed by GHRP therapy, you could save quite a bit of money on your treatment. The average monthly cost of sermorelin or ipamorelin injections is significantly lower than HGH injections. On average, HGH injections cost anywhere from $750 to $2000 per month, depending on the dose and brand of HGH. Sermorelin injections cost about $400 to $750 per month. 

Yes. You cannot, under any circumstances, legally purchase sermorelin, ipamorelin, or any authentic GHRH online or anywhere else without a doctor’s prescription. HGH peptide injections are a type of growth hormone therapy. Like human growth hormone (HGH), you need a doctor's prescription for HGH peptide therapy. Sermorelin and similar growth hormone peptide therapies are only given via injections. You cannot legally obtain GHRP injections without a doctor's prescription.

Sermorelin therapy is given over the course of many weeks – usually for a period of three to six months, depending on your age, gender, presenting symptoms, medical history, and lifestyle.

One of the advantages of sermorelin therapy is that the gains you make tend to remain even after you stop taking sermorelin.

Sermorelin therapy is given over the course of many weeks. Individual results will vary. However, typically it takes 3-6 months to see the most common benefits of sermorelin treatment, such as increased lean muscle mass; reduced body fat; increased bone density and collagen production; increased bone density; enhanced immune system and cardiovascular function, pancreatic and liver function; and optimal increases in energy and vitality.

Depending on your symptoms, growth hormone therapy alone or sermorelin therapy may be an effective treatment. However, studies have shown that there are patients who can benefit from a combined therapy of both used together.

HGH therapy and sermorelin therapy can be used together. In patients whose levels and symptoms cannot be treated by sermorelin alone, your doctor may prescribe combination therapy. But, only your doctor can determine if such combined therapy is right for you.

There are many other HGH peptides similar to sermorelin that may also be prescribed as a potential alternative to HGH therapy. The second most commonly prescribed HGH alternative is Ipamorelin.

Both ipamorelin and sermorelin stimulate the secretion of human growth hormone with few if any negative side effects. They differ only in the length of their respective amino acid chains, and therefore, they interact with different receptor sites in the brain and pituitary.

Written by Author - Authors/Doctors Authors/Doctors - Medically reviewed by   Medical Reviewers Medical Reviewers - Updated on January 19, 2022